This comedy focuses on the bizarre experiences of fresh-faced medical intern John "J.D." Dorian as he embarks on his healing career in a surreal hospital crammed full of unpredictable staffers and patients – where humor and tragedy can merge paths at any time

Joining the rumpled J.D. in his exhilarating brave new world are his college buddy, Chris Turk, an intern with a more elite surgical group, and J.D.'s fellow medical intern, the beautiful and driven Elliot Reid. Keeping the new interns on their toes are: The fatherly chief of medicine, Dr. Bob Kelso); the abrasive, worldly Dr. Perry Cox, and the caring but slightly jaded nurse Carla Espinosa. The hospital janitor also never seems to miss an opportunity to harass his target.